SAINTS will face a Fulham side who must reorganise in the wake of last Saturday's controversial game at West Brom.
Chris Coleman's side was hit with an FA disciplinary charge after referee Mike Dean reported them for harrassment during the 1-1 draw at The Hawthorns.
The Londoners could face a fine of up to £250,000 while striker Andy Cole and midfielder Papa Bouba Diop were both sent off.
Cole was shown the red card for lashing out at Neil Clement after the latter's cynical challenge on ex-Saint Louis Boa Morte, while Diop was dismissed after a clash with Albion defender Darren Purse.
Both serve the second match of a three-game suspension for their dismissals tomorrow.
Right-back Liam Rosenior is also out of tomorrow's game through suspension after he was sent off on his first team debut for an alleged dive at Boston in Wednesday's Carling Cup tie.
Rosenior was always unlikely to play anyway tomorrow with Moritz Volz the first choice right-back.
Coleman was also without midfielders Lee Clark and Claus Jensen at Boston through calf injuries. But influential midfield playmaker Steed Malbranque came through his first start of the season following a groin injury.
The Frenchman, who was once a target of former Saints boss Gordon Strachan, marked his comeback with a goal in Fulham's 4-1 win at the League Two outfit.
Coleman took the chance to experiment with youngsters Malik Buari and Zesh Rehman up front and at centre half respectively at Boston, but they won't start tomorrow.
Neither will former Bolton striker Youri Djorkaeff, who has been training with Fulham this week but is not match-fit.
Edwin van der Sar returns in goal in place of Mark Crossley for Saints' visit while youngster Adam Green is expected to remain at left-back in the absence of American international Carlos Bocanegra, who has a hamstring injury.
Saints head coach Steve Wigley must decide on the fitness of James Beattie, Graeme Le Saux and Anders Svensson - who all missed the midweek Carling Cup win at Northampton through injury - as he seeks to mastermind his club's first win at Fulham since 1947/48. Since then, they have played 13 league and cup matches there.
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