SAINTS visit manager Russell Martin's former side Swansea City with a bit of club history on the line.
Martin's side will record Southampton's longest unbeaten run in Football League history by avoiding defeat.
A win at Liberty Stadium could also see Saints claim second in the Championship by the end of the matchday.
Saints were 4-0 winners last time out against Sheffield Wednesday. Here is how we think Martin will line up his side this time around...
Goalkeeper
Gavin Bazunu now has eight Championship clean sheets this season, from 27 matches. He has also been involved in several Saints goals.
Defenders
Kyle Walker-Peters made the Championship team of the week after Wednesday and will support the centre-back pairing with Ryan Manning on the other flank.
Taylor Harwood-Bellis and Jan Bednarek are constantly among Southampton's top performers and are forming a formidable partnership.
Midfielders
Flynn Downes returns to his former side, where he played under Martin, hoping for a positive reception from his old fans.
He will give Will Smallbone and Stuart Armstrong the license to create, with new signing Joe Rothwell likely waiting in the wings as a substitute.
Attackers
Adam Armstrong has registered more goals and assists combined than any player in the Championship this season.
Che Adams and Ryan Fraser are also in some of their best form in a Saints shirt and give Martin no headaches over who to start in the front three.
Full predicted lineup:
Bazunu; Walker-Peters, Harwood-Bellis, Bednarek, Manning; Downes, Smallbone, S Armstrong; A Armstrong, Fraser, Adams.
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